mardi 26 décembre 2017


Thank you for visiting this site!
Let me briefly explain my situations and activities.

In 2007, after a scientific career as immunologist, I moved to Paris to reflect upon science and human existence. I completed my Master's degree in Philosophy and History of Science at the Université Paris 1 Panthéon-Sorbonne in 2009, and my Doctoral Degree in Scientific Knowledge at the Université Sorbonne Paris Cité in 2016. I was Invited Investigator at the Université François Rabelais from 2016 to 2018.

In 2013, I established the Institute for Science and Human Existence (ISHE). The missions of the Institute are: (1) to popularize science and philosophy, (2) to study scientific problems from the philosophical and metaphysical point of view,  (3) to research on the philosophy as a way of life,  (4) to promote cultural exchange between France and Japan, and (5) to reach an understanding of human existence and eventually to transform our own existence.

I am now based at the ISHE
. My current projects are to write books on immunity and on science and life from the philosophical and metaphysical perspectives.  

Japanese site: サイファイ研究所 ISHE

(July 19, 2020)



Special Issue in the journal Philosophies

Dear Colleagues,

Recent advances in immunology are transforming our view of the immune system and the phenomenon of immunity. For example, the specificity of antigen recognition and the existence of various forms of immunological memory blurs the boundary between adaptive immunity and innate immunity. It has been clarified that the immune system is closely associated, more than ever, with other systems in an organism, such as the nervous system, the endocrine system, and the metabolic system, such that the immune system appears to be coterminous with the organismal whole. Research that traces the phylogenetic tree also provides us food for thought regarding how to interpret the essential feature of the immune system. The current state with this unprecedented new information can be called a “philosophical situation.” We must face these facts anew and re-question the fundamental issues, such as specificity, cellular activation and regulation, self-recognition, innate and adaptive immunity, immunological memory, homeostatic regulation of biological polarity, and the psychoneuroendocrinoimmune network, and how to consider the immune system and the essential feature of immunity. Furthermore, the omnipresence of immunity in the living realm provides an opportunity to think about organisms and life from the perspective of immunity. To advance these processes, both synchronic and diachronic analysis is indispensable. In this special issue of “immunophilosophy,” we aim to review the current state of our scientific understanding of immunity and deepen analyses of individual phenomena within it or immunity in its totality from the perspectives of science, philosophy, history, and metaphysics. In doing so, we hope to stimulate transdisciplinary discussions and set the stage for establishing a new paradigm, which will serve as a guidepost for future research. We welcome the contributions of papers in this direction or from other promising perspectives.

Dr. Hidetaka Yakura
Guest Editor